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Electroacupuncture attenuated cerebral ischemic injury and neuroinflammation through α7nAChR-mediated inhibition of NLRP3 inflammasome in stroke rats

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Academic year: 2020

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Fig. 1 Experimental design. Electroacupuncture stimulus was given at a frequency of 2/15 Hz and an intensity of 1 mA for 30 min for 5 consecutive days.After 24 h of the last stimulus, the rats were subjected to MCAO for 1.5 h and were sacrificed for research at 6 h, 24 h, 3d, 7d after reperfusion
Fig. 2 Effect of cerebral ischemia-reperfusion injury on the expression of NLRP3 inflammasome
Fig. 3 Effect of EA stimulus on the expression of NLRP3 inflammasome.with MCAO group. ** a Representative western immunoblotting analysis of NLRP3, Caspase-1 and IL-1β(n = 4)
Fig. 4 Effect of EA stimulus on the expression ofgroup. Scale bar = 30αRepresentative immunofluorescent staining of α7nAChR
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