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Survivin promoter-regulated oncolytic adenovirus with Hsp70 gene exerts effective antitumor efficacy in gastric cancer immunotherapy

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Academic year: 2020

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Figure

Figure 1: Survivin expression and oncolytic adenovirus replicative activity in cell lines examined
Figure 2: Survivin promoter-regulated oncolytic adenoviruses mediated Hsp70 expression
Figure 3: Specific cytotoxicity of oncolytic adenovirus in gastric cancer cells. (A) The cells were seeded into 96-well plates at a concentration of 104 cells/well and then infected with viruses at MOIs that ranged from 1 to 100 pfu/cell
Figure 4: The efficacy of virus treatments in gastric cancer xenograft models. (A) Nude mice were each implanted with 106 SGC-7901 cells, which formed xenograft tumors 12 days thereafter
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