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Brain tumor is a sequence specific RNA binding protein that directs maternal mRNA clearance during the Drosophila maternal to zygotic transition

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Academic year: 2020

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Figure

Figure 1 BRAT and PUM each associate with hundreds of mRNAs in earlygenes, andmicroarray that were defined as expressed in early embryos, in BRAT RIP or PUM RIP versus Control RIP
Figure 2 PUM- and BRAT-binding motifs.mRNAs with the sequences of therepression by BRAT, but the Box A motifs from (A) Motif enriched among PUM-associated mRNAs, identified by de novo motif discovery
Figure 3 PUM and BRAT motifs are primarily enriched in the 3motif among the subset of BRAT-PUM co-targets, and’UTRs of their associated mRNAs
Figure 4 Enrichment of PUM and BRAT motifs among associatedmRNAs. (A) AUROC plots showing how well the PUM motifdetermined from our RIP-Chip data distinguishes the following setsfrom co-expressed non-targets: BRAT and PUM co-targets, BRAT-onlytargets (BRAT
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