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Pharmacophore modelling and docking studies of pyrrolidinyl pyridone and pyrazinone analogues as prolyl oligopeptidase(POP) inhibitors

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Figure

Figure 1: (a) Pictorial representation of the cubes generated using the QSAR model of most active molecule (21)
Figure 2: Scatter plot of Experimental and Predicted activities of training and  test set molecules
Figure 4: Structure of newly designed molecules

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