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Storti, Andrea Ennio (2018): Dissecting regulatory and expression dynamics during ecdysone signaling in Drosophila melanogaster. Dissertation, LMU München: Fakultät für Chemie und Pharmazie

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Figure

Figure 1: Schematic illustration of transcriptional regulation. Local structure of the chromatin in active enhancers and promoters is characterized by diminished nucleosome occupancy
Figure 2: Schematic illustration of chromatin accessibility assays. DNase I (blue arrows) and Tn5 (green arrows) preferentially target regions of accessible chromatin (active CREs)
Figure 3: Schematic illustration of ecdysone pulses during metamorphosis. Ecdysone dictates the timing of developmental stages
Figure 5: Ecdysone induces similar dynamics at accessibility and expression levels over time
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