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Human Immunodeficiency Virus Persistence and Production in T-Cell Development

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Figure

FIG. 1. Thymocyte development scheme. (A) Combinations of an-tibodies were used to identify thymocytes at five distinct stages of
FIG. 2. X4 HIV-1 replicates in immature thymocytes, while R5 HIV-1 replicates in mature thymocytes in HIV-1-infected SCID-hu mice.Thymocytes were obtained from HIV-1-infected implants in SCID-hu mice at 19 days (NL4-3) and 26 days (JR-CSF) postinfection
FIG. 3. R5 and X4 HIV-1 proviral burdens in thymocyte subsets atdifferent stages of maturation
FIG. 4. HIV-1 coreceptor expression in thymocytes at five devel-opmental stages. CCR5 and CXCR4 expression at stages I-P to IV of
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