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Extracellular matrix and its receptors during development

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Figure

Fig. 1. Illustrationembryonicof Bps integrinandactindistributionin primaryDrosophilacell cultures.Primary Drosophilaembryocul-tures were grown on laminin substratesin the presenceof serumfor 36h
Fig. 2. Schematic representationof in vitro myogenesis.As mononuclear skeletal myob/asts fuse in vitro to form multinucleated myotubes a num-ber of changestake place
Fig. 3. Schemeofits 2 receptor interactionsbetweenthelaminin.'complexwithcomplexesduringepithelialmorphogenesis.The inter-actionsbetweenlamininy1 chain and fragment£8 and integrina6{31 arefairly wellestablished.It is sti/! not very we/! knownhowa-dystroglycanbindsto laminin-J,butcurrentevidencesuggeststhatlaminin-Jfrag-ment£3 bindsto a-dystroglycan.
Fig. 4. Expressionof laminin chains and integrin chains a6 and ~1 during branching epithelial morphogenesisof submandibulargland.Monoclonal antibodiesagamst£3fragmentof Jaminin a 1 cham stains onlv basement membranes of epithelia (AI

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