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Sunitinib Reduces Acute Myeloid Leukemia Clonogenic Cells in Vitro and Has Potent Inhibitory Effect on Sorted AML ALDH+ Cells

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Figure

Figure 1. Antiproliferative effect of Sunitinib on AML cells lines. (a) Chemical structure of Sunitnib malate; (b) Cell proli-feration assay performed using Cell-Titre Blue reagent at 48 h demonstrated a dose-dependent antiproliferative effect on AML cell
Figure 2. Effect of sunitinib on clonogenic cells (a) Sunitinib (Sut) effectively reduces CFC derived from primary AML samples

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