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Nω Nitro Nω’ Substituted Guanidines: A Simple Class of Nitric Oxide Synthase Inhibitors

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Figure

Table 1for most compounds were usually greater than 60%. The details of the compounds synthesized are presented in
Table 1. Nω-nitro-Nω’-substituted guanidines synthesized according to Scheme 1.
Table 2. In vitro activity and selectivity of nitro-guanidines against the isolat- ed isoforms of NOS

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