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Single Base Substitutions in the Capsid Region of the Norovirus Genome during Viral Shedding in Cases of Infection in Areas Where Norovirus Infection Is Endemic

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Figure

FIG. 1. Change in copy numbers of NoVs in feces obtained fromemployees. The copy number of NoV was measured by real-time PCR,
FIG. 2. Phylogenetic tree of NoV GII genotype 4 sequences ob-tained from outbreaks in Toyama prefecture from April 2003 to March
FIG. 3. Alignment of the amino acid sequence of ORF2. Amino acids identical to the consensus sequence are indicated by periods, and onlythe different sequences are included
FIG. 4. Nucleotide sequences of the cloned capsid region. (A) Alignment of cloned nucleotide sequences from positions 41 to 60 of consecutivespecimens of employee a
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