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Patient-derived glioblastoma stem cells are killed by CD133- specific CAR T cells but induce the T cell aging marker CD57

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Figure

Figure 1: Scheme of the AC133-specific CAR and flow cytometric characterization of AC133-CAR expression
Figure 2: AC133-CAR T cells specifically recognize and kill AC133-positive glioma cells in vitro
Figure 3: AC133-CAR T cells show therapeutic efficacy against established, orthotopic GBM-SC-derived glioma xenografts in mice
Figure 4: Expression of T cell exhaustion and senescence markers on AC133-CAR T cells
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