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Sympathetic activation in exercise is not dependent on muscle acidosis Direct evidence from studies in metabolic myopathies

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Figure

Table II. MVC and Duration of Static Handgrip Exercise at 30% MVC in Five Healthy Subjects (Control), in Seven Patients with Myophosphorylase Deficiency (McArdle), in One Patient with Muscle PFKD, and in One Patient with MM
Figure 1. Integrated neurograms of muscle sympathetic nerve activity at rest, during the last 35 s of static handgrip exercise at 30% of maximal voluntary contraction force (MVC) to exhaustion and during recovery from exercise in a healthy subject (Control), a myophosphorylase-defi-cient patient, the MM patient, and the muscle PFKD patient.
Figure 3. Changes in MSNA expressed as bursts per minute (BPM) from rest to handgrip exercise (HG) and from rest to post-handgrip ischemia or nonischemic recovery in one McArdle patient and three healthy control subjects

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