Original Article The negative feedback loop of miR-122 and c-myc in hepatocellular carcinoma
Full text
Figure
Related documents
To evaluate the role of miR-122-3p in the radio- sensitivity of breast cancer cells, MDA-MB-231 cells were transfected with miR-122-3p mimic, inhibitor or control, and the
Taken together, our study found that c-myc could regulate the expression of miR-106b and the suppression of miR-106b expression could inhibit cell proliferation, and
The analysis of the relative expression levels of miR-106b and miR-122 in all clinical stages showed that the relative expression levels of both in the LC tissues and sera of
BCPAP cells were transfected with miR- 200c mimics or miR-200c NC by Lipofectamine 2000 according to the expression level of miR- 200c in cell lines following manual
In the current study, we validated the differen- tial expression of miR-24-3p in HCC tissues and hepatocellular carcinoma cell lines compared with their corresponding
expression 6.3-fold in anti-miR-93 transfected HepG2 cells compared to control cells, and mimic-miR-93 induced miR-93 expression 3.3-fold in mimic-miR-93 transfected SNU449
In this study, we found that c-Myc expression was upregulated by low expression of miR-320a in HCC tissues by IHC assay, and upregulation of miR-320a downregulated the
Our findings demonstrated that BRD7 expression and c-Myc activation forms a negative feedback loop to control the cell proliferation and tumor growth by targeting miR-141..
