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TAZ and YAP are frequently activated oncoproteins in sarcomas

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Academic year: 2020

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Figure

Figure 1: Survival data derived from The Cancer Genome Atlas for undifferentiated pleomorphic sarcoma and dedifferentiated liposarcoma (combined)
Figure 2: YAP and TAZ are widely expressed and activated (nuclear localization) across multiple histological sarcoma types
Figure 3: YAP and TAZ are associated with increased grade. a. TAZ/YAP are only focally and weakly expressed in well-differentiated liposarcoma (grade 1 tumors)
Figure 4: In vitro studies demonstrating that TAZ and YAP are activated oncoproteins in the SK-LMS-1 cell line
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