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Osteopontin promotes epithelial-mesenchymal transition of hepatocellular carcinoma through regulating vimentin

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Academic year: 2020

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Figure

Figure 1: OPN promotes EMT in HCC cells. (A) Representative pictures show the morphological change after overexpression of OPN in HCC cells
Figure 2: OPN binds to vimentin in HCC cells. (A) Identification of OPN-associated factors using immunoprecipitation and mass spectrometry (IP/MS)
Figure 3: OPN increased the stability of vimentin. (A) Overexpression (left two panels) or knockdown (right two panels) of vimentin in HCC cells showed little influence on OPN expression
Figure 4: Vimentin is essential for OPN-induced EMT in HCC. (A) EMT-related markers were detected in MHCC-97L-OPN and HepG2-OPN cells transfected with shVimentin or scrambled shRNA
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