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A systems pharmacology approach to the adenosine A1 receptor

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Figure

Figure 1.2: GPCR structure and activation A.the model GPCR. PDB ID 1F88 (Palczewski et al., 2000).of GPCRs
Figure 1.5: The G protein cycle. An inactive GPCR is coupled to a GDP boundG protein consisting of a Gα and a Gβ γ dimer
Table 1.1: A summary of Gα families and their common roles.
Figure 1.7: The effect of ligands on concentration-response curves.receptor model assumes a dynamic equilibrium between active (R) and inactive receptors(R*)
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