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In vitro antimicrobial and α-glucosidase inhibitory potential of enantiopure cycloalkylglycine derivatives: Insights into their in silico pharmacokinetic, druglikeness, and medicinal chemistry properties

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Figure

Table 1. Antimicrobial (IZD) and α-glucosidase (IC50) inhibitory activity of the synthesized compounds.
Table 3. ADME properties of compounds 1–15 according to pre-ADMET software.
Table 4. Pharmacokinetics, medicinal chemistry and druglikeness of compounds 1–15 according to SwissADME software.
Figure 1. Bioavailability radar of compounds (1–15) using Swiss ADME predictor. The pink area represents the optimal range for each property (LIPO, size, polarity, solubility, saturation and flexibility).

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