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Mechanisms and evolution of resistance to environmental extremes in animals

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Figure

Fig. 1 Representative stress-tolerant model organisms. fish that utilizes type I antifreeze proteins to prevent internal ice formation under freezing temperatures
Fig. 2 Schematic of defense and rescue phases of hypoxic response. Left: the defense phase of hypoxia tolerance begins with the sensing of low-oxygen conditions
Fig. 3 Radiotolerance does not correlate with decreased double-stranded DNA breaks. Left: quantification of DNA double-strand breaks (DSB) per Gray (Gy) of irradiation, normalized for genome size for various radiosensitive and tolerant organisms
Fig. 4 Schematic representation of trehalose’s proposed protective mechanism. Hydrated phospholipid membranes exist in a liquid crystalline state
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