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EOS, an Ikaros family zinc finger transcription factor, interacts with the HTLV 1 oncoprotein Tax and is downregulated in peripheral blood mononuclear cells of HTLV 1 infected individuals, irrespective of clinical statuses

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Figure

Fig. 1 Increased expression of EOS in human T-cell leukemia virustype-1 (HTLV-1)-infected T-cell lines
Fig. 2 Increased expression of EOS after induction of Tax in JPX-9 cells. Expression of EOS in JPX-9 cell line was analyzed by western blotting
Fig. 4 Significant decrease in EOS mRNA load in PBMCs of HTLV-1 infected individuals irrespective of their disease statuses
Fig. 5 Comparison of EOS mRNA levels with tax and HBZ mRNA levels as well as with HTLV-1 PVL among HTLV-1 infected individuals withdifferent clinical statuses

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