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Deregulation of the Egfr/Ras signaling pathway induces age-related brain degeneration in the Drosophila mutant vap

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Figure

Figure 1.Age-related brain degeneration in�vacuolization in the optic lobe (ol) and central brain (cb)
Figure 2.Molecular characterization of theP,expected mutant gene products of the different vap mutant alleles
Figure 4.Functional specificity ofan antibody (ab49) against Csp to vi-sualize the neuropiles
Figure 5.vap interacts with members of the Egfr/Ras pathway. In all panels flies were 18-day-old except in E and F, which were aged forachieved by reducing the dose of Egfr in adulthood ((6 days
+2

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