DEGENERASI SEL
DEGENERASI SEL
PATOLOGI KLINIK (WAT.02.7)
PATOLOGI KLINIK (WAT.02.7)
DR. RENA SUSILO
DR. RENA SUSILO
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DEFINISI
DEFINISI
•
•
Proses kemunduran sel yang berakibat
Proses kemunduran sel yang berakibat
terjadinya perubahan struktur dan fungsi sel
terjadinya perubahan struktur dan fungsi sel
yang bersifat reversibel disebabkan jejas
yang bersifat reversibel disebabkan jejas
non fatal
non fatal
•
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Perbedaan dengan Nekrosis
Perbedaan dengan Nekrosis
Degenerasi
Degenerasi
••
Perubahan pada
Perubahan pada
sitoplasma sel
sitoplasma sel
••
Perubahan bersifat
Perubahan bersifat
reversibel
reversibel
Nekrosis
Nekrosis
•
•
Perubahan pada inti
Perubahan pada inti
sel
sel
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Perbedaan dengan Infiltrasi
Perbedaan dengan Infiltrasi
Degenerasi
Degenerasi
••
Sel terjadi gangguan
Sel terjadi gangguan
metabolisme yang
metabolisme yang
disebabkan jejas non
disebabkan jejas non
fatal
fatal
Tampak perubahan
Tampak perubahan
Infiltrasi
Infiltrasi
••
Terjadi gangguan
Terjadi gangguan
sistemik yang
sistemik yang
berakibat pada sel
berakibat pada sel
••
Contoh : Infiltrasi
Contoh : Infiltrasi
glikogen intrasel pada
glikogen intrasel pada
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Jenis Degenerasi Sel
Jenis Degenerasi Sel
1
1.. D
Deeg
geen
neerraassi
i A
Allb
bu
um
miin
no
ossaa
2
2.. D
Deeg
geen
neerraassi H
i Hiid
drro
op
piik
k
3
3.. D
Deeg
geen
neerraassi H
i Hiiaalliin
n
4
4.. D
Deeg
geen
neerraassi
i M
Mu
ucciin
n
5
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1. Degenerasi Albumin
1. Degenerasi Albumin
•
•
Sel yang terkena degenerasi
Sel yang terkena degenerasi didapatkan granula-
didapatkan
granula-granula
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Penyebab Degenerasi Albumin
Penyebab Degenerasi Albumin
•
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Jaringan yang sering terkena
Jaringan yang sering terkena
Degenerasi Albumin
Degenerasi Albumin
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2. Degenerasi Hidropik
2. Degenerasi Hidropik
•
•
Degenerasi hidropik = degenerasi Albumin
Degenerasi hidropik = degenerasi Albumin
(bengkak keruh)tetapi lebih berat
(bengkak keruh)tetapi lebih berat
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3. Degenerasi Hialin
3. Degenerasi Hialin
•
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3. Livor Mortis
3. Livor Mortis
•
•
Disebut Juga BERCAK MAYAT
Disebut Juga BERCAK MAYAT
•
•
Terdapat bintik-bintik merah kebiruan pada
Terdapat bintik-bintik merah kebiruan pada
bagian bawah tubuh maya
bagian bawah tubuh mayatt
•
•
Terjadi 2
Terjadi 2
– –3 jam setelah kematian
3 jam setelah kematian
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4. Putrefaction
4. Putrefaction
•
•
Disebut juga
Disebut juga PEMBUSUKAN MAYAT
PEMBUSUKAN MAYAT
•
•
Sangat dipengaruhi adanya bakteri ditubuh
Sangat dipengaruhi adanya bakteri ditubuh
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5. Post Mortem Clot
5. Post Mortem Clot
•
•
Disebut juga JENDALAN DARAH MAYAT
Disebut juga JENDALAN DARAH MAYAT
•
•
Jendalan darah pada mayat mudah ditarik dari
Jendalan darah pada mayat mudah ditarik dari
dinding pembuluh darah --- tidak melekat
dinding pembuluh darah --- tidak melekat
••
