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Patient Label

Admission/Condition/Diagnosis

Admission: Admitting Physician Attending Physician Assign to Inpatient Status Transfer to ___________________

Level of Care: Physician MUST document in notes the risk, severity, and skilled nursing need of the patient to justify the status below.

ICU Stroke unit

Diagnosis: Ischemic Stroke tPA Given

Condition: Critical Stable Guarded

Consult neurologist (Reminder: Physician to Physician is required)

Vital Signs

For ICU Patients

Vital Signs including abbreviated NIHSS for the first 24 hours. (Q15MIN for 2 hours, then Q30 min for 6 hrs, then QHR for 16 hrs) + Vital Signs & Neuro checks Q1hr and NIHSS Qshift, with neurological changes and at discharge after the first 24 hours

For Non ICU Patients

Vital Signs including abbreviated NIHSS for the first 24 hours.(Q 15min for 2 hours, then Q 30min for 6 hours, then QHR for 16 hours)

+ Vital Signs & Neuro checks Q4hr and NIHSS Qshift, with neurological changes and at discharge after first 24 hours

Core Measure Orders To Include: Mechanical VTE Prophylaxis

Core Measure Compliance Orders ( By checking you are ordering the orders listed on page 6)

MUST order Intermittent Pneumatic Compression ( IPC) or select or document

contraindication

Sequential Compression Device Knee High

No Mechanical Prophylaxis due to:

Amputee Congestive heart failure Patient non-compliant-refused intervention/support.

Mechanical prophylaxis refused (Required)

Right AKA Burn to lower limb

Left AKA Dermatitis o Intermittent pneumatic calf-thigh compression

Right BKA Hypervolemia o Venous foot pump

Left BKA Deformity of leg

Injury to lower extremity Sensory neuropathy

Peripheral Vascular Disease Suspected deep vein thrombosis of lower extremity

Peripheral ischemia Clouded consciousness

Vascular insufficiency of limb Surgical procedure of lower extremity

Patient enrolled in clinical trial Edema of leg

Lower limb ischemia

History of occlusive disease of artery of lower extremity At risk for falls

Comfort care management Aspiration Precautions

PHYSICIAN MUST INITIAL ALL PAGES THAT ARE NOT SIGNED:

Acute Ischemic

Stroke with tPA

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Patient Label

Core Measure Medications

A.

Antiplatelet

Do not give antiplatelet for 24 hours post TPA infusion and no hemorrhage on repeat imaging study

Aspirin 81 mg 325 mg Oral Daily to start in 24 hours or Aspirin 300 mg Suppository PR daily for NPO pt

Dipyridamole Aspirin [Aggrenox] 200mg-25mg SR Cap PO BID to start in 24 hours or Aspirin 300 mg Suppository PR daily for NPO pt Clopidogrel [Plavix] Tab 75mg Oral Daily to start in 24 hours or Aspirin 300 mg Suppository PR daily for NPO pt

Medication not needed/indicated (Document reason)

B.

Anticoagulant: For atrial fibrillation or atrial flutter (current or history of)

Do not give anticoagulant for 24 hours post TPA infusion and no hemorrhage on repeat imaging study

Warfarin [Coumadin] mg Oral Daily to start tomorrow at 2100 Medication not needed/indicated

+ Other Anticoagulant/Antithrombotic Medications

Enoxaparin [Lovenox] and Heparin are contraindicated if patient prescribed any non-warfarin anticoagulants including the VTE

Prophylaxis dose.

Dabigatran [Pradaxa] Cap 150mg oral BID to start in 24hrs.

Dabigatran [Pradaxa] Cap 75mg oral BID, if CrCl is 15-30ml/min, to start in 24hrs. Rivaroxaban [Xarelto] Cap 20mg oral Daily, to start in 24hrs.

Rivaroxaban [Xarelto] Cap 15mg oral Daily, if CrCl is 15-30ml/min, to start in 24hrs.

Reasons for not administering antithrombotic/anticoagulant (by end of day 2)

Bleeding Platelet count below reference range

Hemorrhagic cerebral infarction Blood coagulation disorder due to liver disease Anterior cerebral circulation hemorrhagic infarction Blood coagulation disorder

Posterior cerebral circulation hemorrhagic infarction Warfarin therapy started

Renal impairment Refusal of treatment by patient

Medical contraindication Surgical contraindication

Additional reasons for Patient not receiving therapy: Pateint enrolled in clinical trials

comfort measures only

Patient admitted for elective carotid intervention procedure

PHYSICIAN MUST INITIAL ALL PAGES THAT ARE NOT SIGNED:

ORDERSET#: ST-BH08 Published: v-

4

April

15

, 2014

Approved: FEBRUARY 2014

Page 2 of 6

Acute Ischemic

Stroke with tPA

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Patient Label

C.

VTE Prophylaxis (Physician should reassess daily)

If GFR < 30 ml/min, reduce Enoxaparin dose to 30 mg subq daily

Do not give anticoagulant for 24 hours post TPA infusion and no hemorrhage on repeat imaging study

Enoxaparin [Lovenox] 40 mg 30mg subq daily to start in 24 hours Exclusion Criteria for VTE Prophylaxis (Check all that apply)

Anticoagulation allergy Blood coagulation disorder due to liver disease Acute spinal cord injury Heparin induced thrombocytopenia Platelet count below reference range Indwelling epidural catheter

Blood coagulation disorder Renal impairment Lumbar puncture, spinal anesthesia,

or epidural removed within the last 2 hours Hemorrhagic cerebral infarction Refusal of treatment by patient

Bleeding Patient enrolled in clinical trial Uncontrolled or severe hypertension

Anticoagulation not tolerated Comfort care management Hypersensitivity to anticoagulants D. Statin or Other Cholesterol Reducing Medications

For LDL greater than or equal to 100 and/or pt on lipid lowering agent prior to admission

Simvastatin [Zocor] Tab 20mg oral nightly 40mg oral nightly Other Cholesterol Reducing Medications

Atorvastatin [Lipitor] Tab 20mg oral nightly 40mg oral nightly 80mg oral nightly Rosuvastatin [Crestor] Tab 40mg oral nightly

Niacin Timed- Release Cap + Simvastatin [Zocor]

Niacin Timed – Release Cap 500mg oral nightly 750mg oral nightly 1000mg oral nightly + Simvastatin [Zocor] 10mg oral nightly 20mg oral nightly

Ezetimibe [Zetia] + Simvastatin [Zocor] Ezetimibe [Zetia] 10mg oral nightly

+ Simvastatin [Zocor] 10mg oral nightly 20mg oral nightly

Acute Ischemic

Stroke with tPA

(4)

Patient Label

Medications

Blood Pressure Medications (Select one only)

Initiate if SBP greater than 180 mmHg or DBP greater than 105 mmHg on 2 readings 10 minutes apart. Target SBP 160 - 180 mmHg, DBP 90 - 105 mmHg during and 24HR post TPA.

Labetalol [Normodyne] 10MG 20MG 40MG IV PRN. May repeat Q10MIN to max of 300 mg.

DO NOT give if pulse less than 60 BPM. Give over 1 min. Labetalol [Normodyne] Infusion

-Labetalol [Normodyne] Injection 10MG 20MG 40MG IV bolus. Give over 1 min.

DO NOT give if pulse less than 60 BPM. -Labetalol [Normodyne] Infusion 2MG/MIN 4MG/MIN 8MG/MIN IV (Dose range 2 – 8 mg/min) DO NOT give if pulse less 60 BPM

niCARdipine [ Cardene ] Infusion Start IV infusion at 5mg/hour. Titrate by 2.5mg/hour Q5MIN up to 15mg/hour to target BP, then decrease to 3mg/hour.

.

Stroke Work-Up Studies

Hemoglobin A1C, Routine Once

Trans-thoracic Echo order with doppler,

colorflow and bubble study Interpreting Cardiologist Ultrasound Carotid Duplex, bilateral

CT head Without contrast With contrast MRI head Without contrast With contrast MRA Brain Without contrast With contrast

IV Fluids

Start Saline Lock + Maintain Saline Lock + Saline Flush

Sodium Chloride 0.9% [Normal Saline] 50ml/hr 75 ml/hr 100ml/hr 125ml/hr Other ml/hr Sodium Chloride 0.45% [1/2 Normal Saline] 50ml/hr 75 ml/hr 100ml/hr 125ml/hr Other ml/hr

PHYSICIAN MUST INITIAL ALL PAGES THAT ARE NOT SIGNED:

ORDERSET#: ST-BH08 Published: v-

4

April

15

, 2014

Approved: FEBRUARY 2014

Page 4 of 6

Acute Ischemic

Stroke with tPA

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Patient Label

Consults

Diabetic Education Consult

For Intracranial Hemorrhage after Alteplase Infusion

Administer Cryoprecipitate 5 units/pack Single unit + Type + Screen

+ Transfuse Cryoprecipitate

+ Verify patient has signed informed consent for blood and blood products Administer Platelet Pheresis 1 unit

+ Type + Screen

+ Transfuse Platelet Pheresis

+ Verify patient has signed informed consent for blood and blood products

Administer aminocaproic acid [Amicar] 5g/250ml NS IV over 1 hour followed by 5g/250ml NS IV at 50ml/hr x 5 hours or until bleeding ceases

PHYSICIAN MUST INITIAL ALL PAGES THAT ARE NOT SIGNED:

Acute Ischemic

Stroke with tPA

(6)

Patient Label

Core Measure Compliance orders for AIS with TPA

Medication communication: Do not give Antithrombotic, Antiplatelet, Anticoagulants or NSAIDs for 24 hours post-TPA

infusion & no hemorrhage on repeat imaging study. Refer to the Antiplatelet and Anti-coagulant medication list on the

utilities menu under patient education.

Notify physician if patient exhibits any of the following during or within 24 hours after Alteplase administration: acute

neurological deterioration, new headache, acute hypertension, nausea and vomiting and a 4 point or more increase in the

previous NIHSS score:

a.

Suspect intracranial hemorrhage

b.

If Alteplase is infusing – Stop immediately

c.

Notify physician immediately

d.

STAT lab: PT/Aptt, Platelet Count, fibrinogen, type and screen

e.

STAT non contrast CT of head.

Notify Physician if Temp > 99.4 F, Respiratory rate > 24, Systolic BP < 110 or > 180 mmHg, Diastolic BP < 60 or > 105 mmHg,

Pulse < 50 or > 110, Blood Glucose > 140

Nursing: Order a non contrast CT of head 24 hrs post TPA.

Bedrest

Seizure/fall risk precautions

Elevate HOB > 30 degrees

Document fall risk assessment

NPO until after tPA infused then continue NPO until patient passes dysphagia screen or formal swallow study. If pt fails,

order nutrition consult.

Notify physician if patient passes dysphagia screen for diet order

Maintain O2 Sat > 92%. If < 92%, start O2 at 2 liters/min via nasal cannula and notify MD

Smoking cessation order : Give pt advice/counseling

Dietary consult: For caloric and dietary orders

Document that the "Stroke Information & Education for You" booklet and each component of its content was discussed

with patient / family / caregiver

CBC with auto diff in AM

Fasting Lipid panel in AM

Comprehensive metabolic panel in AM

RN case mgmt / Social Svc consult: To assess/assist with patient needs and initiate discharge planning

Pastoral care consult: For patient spiritual assessment as needed

Physical therapy consult : evaluate and treat

Occupational therapy consult : evaluate and treat

Speech therapy order to evaluate and treat and Bedside swallow evaluation

(on weekends, call facility operator to connect you to speech voicemail and leave message)

PHYSICIAN’S PRINTED NAME, SIGNATURE and ID# DATE: TIME:

ORDERSET#: ST-BH08 Published: v-

4

April

15

, 2014

Approved: FEBRUARY 2014 Page 6 of 6

Acute Ischemic

Stroke with tPA

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