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Leukemic transformation driven by an ASXL1 mutation after a JAK2V617F-positive primary myelofibrosis: clonal evolution and hierarchy revealed by next-generation sequencing

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Academic year: 2020

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Figure

Figure 1 Histologic and radiologic studies at the time of leukemic transformation. (A) BM biopsy showing immature myeloid proliferationwithout segmentation (blasts >20%) and dysplastic megakaryocytes
Figure 2 Clonal progression from diagnosis of PMF to leukemic transformation and death

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