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A photoactivatable small molecule inhibitor for light controlled spatiotemporal regulation of Rho kinase in live embryos

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Figure

Fig. 1. Synthesis of a photoactivatable Rho kinase inhibitor. ((NPOM) on the indole nitrogen of Rockout (RO)
Fig. 2. In vivo efficacy of caged Rockout.(A-C)Stage 39 Xenopus embryos were exposed to
Fig. 3. Caged Rockout locally affects gut epithelial morphogenesis in a light-dependent manner
Fig. 4. Rho kinase plays different roles on contralateral sides ofthe gut. rinsed, and kept in the dark (A) or irradiated on the left (B) or right (C)side of the prospective gut, as in Fig

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