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SPHK1 regulates proliferation and survival responses in triple- negative breast cancer

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Figure

Figure 1:SPHK1 expression in breast tumors. (A) SPHK1mRNA expression in human breast tumors and paired adjacent normal breast tissues by real-time PCR
Figure 3:Inhibition of SPHK1 activity induces apoptosis and inhibits proliferation of breast cancer cells
Figure 4: Inhibition of SPHK1 activity impairs colony formation and breast tumor formation by MDA-MB-231 cells in immunodeficient mice
Figure 5:SKI-5C inhibits the serum-dependent activation of ERK1/2 and AKT signalling and S1P export
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