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Mutant p53 confers chemoresistance in non-small cell lung cancer by upregulating Nrf2

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Figure

Table 1: Relationships between Nrf2 mRNA expression and clinical-pathological parameters NSCLC patients
Figure 1: Nrf2 transcription is suppressed by wild-type p53. A. Western blotting analysis for Nrf2, HO-1, and NQO1 expression in various lung cancer cell lines, β-actin was used as a loading control
Figure 2: Nrf2 transcription is down-regulated by wild-type p53 via decreased Sp1 binding to the Nrf2 promoter
Figure 3: Nrf2 expression is responsible for cisplatin sensitivity in lung cancer cells
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