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Alignment free sequence comparison: benefits, applications, and tools

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Figure

Fig. 1 Alignment-free calculation of the word-based distance between two sample DNA sequences ATGTGTG and CATGTG using theEuclidean distance
Fig. 2 Alignment-free calculation of the normalized compressiondistance using the Lempel–Ziv complexity estimation algorithm.Lempel–Ziv complexity counts the number of different words insequence when scanned from left to right (e.g., for s = ATGTGTG,Lempel
Table 1 Alignment-free sequence comparison tools available for next-generation sequencing data analysis
Table 1 Alignment-free sequence comparison tools available for next-generation sequencing data analysis (Continued)
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