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Bidirectional transcription initiation marks accessible chromatin and is not specific to enhancers

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Figure

Fig. 1 Bidirectional transcription initiates around DHSs but is not a specific mark of active enhancers
Fig. 2 Chromatin-defined enhancer marks rather than transcription arethe median reporter activity for all scrambled control sequence assays inK562 cells.indicative of enhancer activity
Fig. 3 Stable transcription is not indicative of enhancer activity.level of DHS signal of chromatin state loci and bidirectionally transcribed-defined enhancers and transcription initiation from the nearest annotatedregulatory region) is then correlated wi
Fig. 4 Mature eRNAs do not show signatures of selection within thehuman population. Odds ratios of frequencies within the deCODEpopulation [49] for rare (<1.5%) and common (>5%) derived allelescompared between exonic and intronic sequences for transcriptso

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