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Endocytosis of HIV 1 activates plasmacytoid dendritic cells via Toll like receptor– viral RNA interactions

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Academic year: 2020

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Figure

Figure 1pDC activation in response to HIV-1. BDCA-4+ pDCs were cultured in the presence of various doses of HIV-1MN (ng p24CA/ml)
Figure 3Inhibition of fusion with plasma membrane and endocytosis. (
Figure 4Inhibition of endosomal acidification/maturation. pDCs
Figure 5HIV RNA stimulates pDCs but not MDCs. (A) Flow cytometry–sorted pDCs were exposed overnight to recombinant wild-type or mutant NC SSHS/SSHS HIV-1NL4-3 at the doses of 900 or 300 ng p24CA Eq/ml
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