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MMP13 is a critical target gene during the progression of osteoarthritis

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Academic year: 2020

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Figure

Table 1 Breeding of Col2CreER;Mmp13(fx/fx miceMmp13Col2ER).
Figure 1 Decelerated osteoarthritis progression inThe tibia cartilage area was increased 21% in16 weeks post-surgery
Figure 2 Decelerated osteoarthritis progression inImmunohistochemistry (IHC) of Col2 was performed to assess its protein level
Figure 3 CL82198 prevents and decelerates MLI-induced osteoarthritis progressionshowed that CL82198 could inhibit > 90% MMP13 activity produced by BMP-2-treated primary chondrocytes
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