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Efficient reengineering of meso-scale topologies for functional networks in biomedical applications

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Academic year: 2020

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Figure

Fig. 1 Structures of functional
Fig. 2 Scheme of upstream/downstream inhibition. (a) Inhibitor acting on a signalling pathway upstreamand downstream of a ‘merger’ node (black circle)
Fig. 3 Effects of inhibition on induced phosphorylation. (phosphorylations for all combinations of stimuli is different with and without inhibition indicating that theinhibition acts upstream of the joint node of the stimulation pathways
Fig. 4 Network structures and correlated stimulation. (lated. (a) The stimulations of proteins k and l are corre-b) The stimulations of proteins k and l are not correlated.

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