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Systemic and central nervous system metabolic alterations in Alzheimer’s disease

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Figure

Table 1 Clinical characteristics of the cohort
Fig. 1 Study design and metabolic profiling workflow. Plasma and CSF samples were collected concomitantly, from the same subject
Fig. 2 Systemic and central nervous system alterations in AD in the energy metabolism hub; the TCA cycle and its anaplerotic pathways (i.e.,significant higher or lower concentrations in AD vs controlamino acid metabolism, glycolysis and beta-oxidation)
Fig. 3 Systemic and central nervous system alterations in products of tryptophan breakdown in AD
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