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Artesunate suppresses tumor growth and induces apoptosis through the modulation of multiple oncogenic cascades in a chronic myeloid leukemia xenograft mouse model

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Figure

Figure 1G, JAK2 was constitutively active in KBM-5
Figure 1: (Continued) (F) KBM-5 cells (1 × 106 cells/well) were treated with various indicated concentrations of ART for 4 h
Figure 2: ART induces apoptosis by PARP cleavage through activation of caspase-3. (A)cells/well) were treated with indicated concentrations of ART for 24 h
Figure 3: ART and chemotherapeutic agents induce apoptosis. (A) Inhibition of bcl-2, bcl-xL, and survivin mRNA expressions by ART in KBM-5 cells
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