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Epithelial mesenchymal transition can suppress major attributes of human epithelial tumor initiating cells

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Figure

Figure 2Opposing phenotypes and distinct gene programs expressed by 2 clonal populations derived from PC-3 cells
Figure 3E-cadherin–positive PC-3 cells show an enhanced anchorage-independent growth and a stronger expression of a self-renewal gene program
Figure 4Overexpression of Snai1 in PC-3/Mc cells induces EMT and suppresses anchorage-independent growth and the expression of a self-renewal
Figure 5Constitutive overexpression of Snai1 inhibits local growth, metastatic spread, and distant organ colonization of PC-3/Mc cells
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