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FGF signaling directs a center to pole expansion of tubulogenesis in mouse testis differentiation

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Figure

Fig. 2. Defective maintenance of high-level Sox9 middle segment explants at 30 hours is set as 100% (19.6expression andreduced number of SOX9-positive cells in the pole segmentexplants
Fig. 3. A segment and reconstruction culture assay of the anteriorand posterior pole segments with the middle segment of XYreconstruction of the ROSA26:anterior/posterior segments of the XY genital ridges isolated at 12-14 ts.In B, phase-contrast images sh
Fig. 3E), suggesting testis-specific vasculogenesis (Brennan et al.,
Fig. 5. Exogenous FGF9 supply rescues defective tubulogenesisof pole segment explants of XY genital ridges.immunostaining of the segment explants (12 ts) treated with orwithout FGF9 (50 ng/ml) for the initial 24 hours (total 5 days culture)
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