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Rapid reprogramming of epigenetic and transcriptional profiles in mammalian culture systems

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Figure

Figure 1 (See legend on next page.)
Figure 2 Cell culture-induced 5hmC loss occurs genome-wide and does not reflect changes in 5mC
Figure 3 Global loss of 5hmC and locus-specific gains in 5mC suggest loss of demethylase activity in culture
Figure 4 Change in cell state accompanies adaptation of cells to culture. (a)in MEF tissue (blue) and cultured (orange) cells

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