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Clinical utility of the oral JAK inhibitor tofacitinib in the treatment of rheumatoid arthritis

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Academic year: 2020

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Figure

Figure 1 Intracellular signaling pathways. Notes: Intracellular pathways offer many options for the inhibition of cytokine signaling
Figure 2 The JAK–STAT intracellular signaling pathway. Notes: JAK is involved in the intracellular signal transduction pathways via STATs
Table 1 Summary of the Phase II and Phase III studies conducted on tofacitinib in RA

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