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Update on developments with SGLT2 inhibitors in the management of type 2 diabetes

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Figure

Figure 1 Renal tubular reabsorption of glucose.Notes: Most of the glucose in the glomerular filtrate is reabsorbed by SGLT2 in the proximal convoluted tubule and the remainder is reabsorbed by SGLT1 in the distal straight segment of the tubule, so virtuall
Figure 2 Renal glucose transport.Notes: Glucose and sodium (1:1) enter the renal tubule cells with assistance from glucose transport proteins
Figure 3 Structure of phlorizin and candidate SGLT2 inhibitors.Abbreviation: SGLT, sodium glucose co-transporter.
Figure 4 (Continued)
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