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3D conductive nanocomposite scaffold for bone tissue engineering

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Table 1 concentration of poly(3,4-ethylenedioxythiophene) poly(4-styrene sulfonate), gelatin, and bioactive glass nanoparticles in the aqueous solution
Figure 1 schematic diagram of the preparation of three-dimensional scaffolds with the freeze-drying method.Notes: 0 P, 0.1 P, and 0.3 P represent the scaffolds prepared from 0%, 0.1%, and 0.3% (w/w) poly(3,4-ethylenedioxythiophene) poly(4-styrene sulfonate) in the mixture of 10% (w/v) gelatin and 30% (w/v) bioactive glass nanoparticles.Abbreviations: 3D, three dimensional; Bag, bioactive glass nanoparticles; eDc, 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride; gel, gelatin; Nhs, N-hydroxysuccinimide; PeDOT:Pss, poly(3,4-ethylenedioxythiophene) poly(4-styrene sulfonate).
Figure 2 (A) chemical structure of poly(3,4-ethylenedioxythiophene) poly(4-styrene sulfonate)
Figure 4 The X-ray diffraction pattern of the 0.3 P scaffold. No diffraction peak in the spectra indicates an amorphous structure of bioactive glass nanoparticles in the composition.Notes: 0.3 P represents the scaffolds prepared from 0.3% (w/w) poly(3,4-ethylenedioxythiophene) poly(4-styrene sulfonate) in the mixture of 10% (w/v) gelatin and 30% (w/v) bioactive glass nanoparticles.
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