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Proteolysis of MDA5 and IPS 1 is not required for inhibition of the type I IFN response by poliovirus

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Academic year: 2020

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Figure

Fig. 1 Poliovirus infection fails to induce a type I interferon response inbars indicate the standard error of the results from triplicate wells
Fig. 2 Poliovirus infection inhibits the ability of cells to respond to dsRNA.above. Total RNA was isolated and analyzed by qRT-PCR for IFN- a
Fig. 3 ATF-2 and NF-κB are activated in poliovirus-infected cells. a. Phosphorylation of ATF-2
Fig. 4 IRF-3 is not activated in poliovirus-infected cells.ISG54 mRNA relative to uninfected controls is shown
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