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Studies on Formulation and Evaluation of Ethyl Cellulose Based Extended Release Metformin Hydrochloride Matrix Tablets

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Figure

Table 2: Physical and chemical parameters of formulated
Table 4: Comparative in vitro release profiles on metformin hydrochloride matrix tablet formulations (F1 to F4) and reference standard (F5M)*
Table 5: Regression coefficient values (R2) of selected sustained release matrix tablets of metformin hydrochloride (formulations F3 and FM)
Fig. 3: Plot of stability studies on in vitro release profile at room temperature (25°C±2°C and 60 %±5% RH) and accelerated temperature (40°C±2°C and 75±5% RH) in simulated gastric fluid (pH 1.2-acid buffer) (for first 2 hrs) tablet formulations F3 for 6 months
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