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Berberine Protects Glomerular Podocytes via Inhibiting Drp1-Mediated Mitochondrial Fission and Dysfunction

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Figure

Figure 1. Effects of BBR on PA-induced podocyte injury and apoptosis. (A) SDs and markers of podocyte dedifferentiation were analyzed by fluorescence of chromatin in nucleus and autophage were observed using TEM
Figure 2. BBR inhibited PA-induced mtROS production and mitochondrial dysfunction in podocytes
Figure 3. BBR inhibited PA-induced mitochondrial fragmentation in podocytes. (A) Mitochondrial morphology was observed by TEM and assessed by aspect ratio and form factor using Image J from three independent experiments (>100 mitochondria)
Figure 4. BBR prohibited PA-induced mitochondrial fission via regulating Drp1 in podocytes
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