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GERMAN HEART CENTER MUNICH, NOVEMBER 4 AND 5, 2011

MAC2011

TABLE OF CONTENTS

WELCOME

MAC2011GERMAN HEART CENTER MUNICH, NOVEMBER 4 AND 5, 2011

Dear colleagues,

The significant improvement of diagnostic and therapeutic options for aortic diseases today enables us to treat even very complex lesions by open, endovascular or combined means. There is no doubt that vascular and cardiothoracic surgeons should cooperate rather than compete in this field in order to offer an optimal treatment to their patients. Since these often elderly patients suffer from many co-morbidities a multidisciplinary access including further specialties is mandatory for the clinical success.

For this reason, the Munich Centre for Aortic Diseases (MCA) was founded in 2011. This alli-ance of the department for Vascular Surgery at the “Klinikum rechts der Isar (MRI)” and the department of Cardiovascular Surgery at the German Heart Center Munich (DHM) coopera-tes very closely with other specialities like anesthesia, radiology, cardiology and others at both locations. Since the progress in the management of patients with aortic diseases needs a continuous exchange of data, experiences and skills the Munich Centre for Aortic Disea-ses (MCA) is happy to invite you to the 1st Munich Aortic Conference (MAC).

Our meeting aims to provide an overview of the current treatment options for lesions from the ascending aorta down to the aortic bifurcation. A first-class international faculty will report about the latest advances and future opportunities in open and endovascular aortic surgery. In addition the scientific program offers new insights of translational aortic research including data from vascular biology, biological imaging and computer simulation modalities. The 1st Munich Aortic Conference will be held under the patronage of the German Vascular Society (DGG) and the German Society for Cardiovascular Surgery (DGTHG). We look forward to welcoming you to Munich.

Prof. Dr. Hans-Henning Eckstein

Head of the Department for Vascular Surgery Klinikum rechts der Isar (MRI)

Technical University of Munich (TUM)

Prof. Dr. Rüdiger Lange

Head of the Department for Cardiothoracic Surgery at the German Heart Center Munich Technical University of Munich (TUM)

Welcome 3

MAC-Program, Friday, November, 4 4 - 7

MAC-Program, Saturday, November, 5 8 - 11

Faculty 13

Sponsors and Exhibitors 15

Symposia and Workshops 16

Directions 17

General Information 18 - 19

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GERMAN HEART CENTER MUNICH, NOVEMBER 4 AND 5, 2011

MAC2011 MAC2011GERMAN HEART CENTER MUNICH, NOVEMBER 4 AND 5, 2011

09.00 WELCOME H.-H. Eckstein, Munich, Germany

R. Lange, Munich, Germany 09.05 – 10.30 SESSION I:

Aortic root and valve

Chairs:

R. Lange, Munich, Germany J. S. Rankin, Nashville, USA

KEYNOTE LECTURE:

Principles of aortic valve surgery

G. El Khoury, Brussels, Belgium

Aortic root reconstruction – evolution of the David procedure

R. Lange, Munich, Germany

Conversion to autologous surgery for aortic valve disorders

J. S. Rankin, Nashville, USA

David vs Yacoub operation: early results and long time follow up

W. Harringer, Braunschweig, Germany

Root surgery in Marfan‘s disease R. Leyh, Würzburg, Germany

Ascending aorta: replacement versus reduction plasty

U. Herold, Munich, Germany

Panel discussion

10.30 – 11.00 COFFEE BREAK

11.00 – 12.30 SESSION II:

Open and endovascular options for the aortic arch

Chairs:

K. Ivancev, London, UK A. Khoynezhad, Los Angeles, USA

KEYNOTE LECTURE:

Evolution of aortic arch replacement

A. Khoynezhad, Los Angeles, USA

Hybrid techniques “on pump” B. Voss, Munich, Germany

Hybrid techniques “off pump” P. Kasprzak, Regensburg, Germany

Tips and tricks for the hybrid approach of the arch

J. P. Becquemin, Paris, France

Long term results and predictors of late failure after supraaortic hybrid procedures

D. Böckler, Heidelberg, Germany

Complete endovascular grafting for arch aneurysms and thoracoabdominal aortic aneurysms K. Ivancev, London, UK Panel discussion 12.45 – 13.45 Main lecture hall LUNCH SYMPOSIUM I:

MEDTRONIC: EVAR – Standard of care!

Chairs:

D. Böckler, Heidelberg, Germany G. Torsello, Munster, Germany

A paradigm shift in treatment of abdominal aneurysms

F. Marquardt, Bremen, Germany

Clinical Update Endurant D. Böckler, Heidelberg, Germany

Pushing the limits of EVAR G. Torsello, Munster, Germany 12.45 – 13.45

Meeting room

LUNCH SYMPOSIUM AND WORKSHOP II:

VASCUTEK

Thoraflex – the next generation of thoracic stentgrafts

M. Jacobs, Maastricht, NL / Aachen, Germany

Fenestrated Anaconda™ – first experiences P. Berg, Kevelaer, Germany

Hands-on-workshop: Anaconda™ for AAAs P. Berg, Kevelaer, Germany J. Schmidt, Vascutek Deutschland GmbH

FRIDAY, NOVEMBER 4, 2011

FRIDAY, NOVEMBER 4, 2011

5 4

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GERMAN HEART CENTER MUNICH, NOVEMBER 4 AND 5, 2011

MAC2011 MAC2011GERMAN HEART CENTER MUNICH, NOVEMBER 4 AND 5, 2011

14.00 – 15.35 SESSION III:

Thoracic and thoracoabdominal aneurysm (TAA/TAAA)

Chairs:

H.-H. Eckstein, Munich, Germany M. Jacobs, Maastricht, NL / Aachen, Germany

KEYNOTE LECTURE:

Open surgery with distal perfusion and neuromonitoring remains the first choice for patients with TAA and TAAA related to connective tissue diseases

M. Jacobs, Maastricht, NL / Aachen, Germany

Indications and technical aspects for open and hybrid repair of thoracoabdominal aortic aneurysms

R. Chiesa, Milano, Italy

Clinical implications of the collateral network concept of the spinal cord perfusion

C. Etz, New York, USA

The risk of spinal cord ischemia during TEVAR: how could we prevent it?

C. Setacci, Perugia, Italy

Mid- and long term outcomes after more than 1000 TEVARs – the influence of the underlying disease

M. Thompson, London, UK

Treatment of chronic expanding type B dissections with fenestrated and branched grafts – is it feasible?

E. Verhoeven, Nuremberg, Germany

Extensive experience from complex EVARs, calls for new classification of juxtarenal, pararenal and thoracoabdominal aneurysms

K. Ivancev, London, UK

Panel discussion

15.35 – 16.00 COFFEE BREAK

FRIDAY, NOVEMBER 4, 2011

FRIDAY, NOVEMBER 4, 2011

16.00 – 17.40 SESSION IV:

Supra- and infrarenal abdominal aortic aneurysm (AAA)

Chairs:

R. Greenhalgh, London, UK J. B. Ricco, Poitiers, France

KEYNOTE LECTURES:

Long term results after open and endovascular repair – lessons from the European RCTs

The RCTs comparing open and endovascular AAA repair are good but reach the wrong conclusions: EVAR is preferable in all patients

R. Greenhalgh, London, UK F. Veith, New York, USA

Open repair of AAA: evidence-based perioperative risk adjustment and fast track management

S. Debus, Hamburg, Germany

Surveillance after EVAR and open repair for AAA – recommendations from the European Society for Vascular Surgery (ESVS)

J. Ricco, Poitiers, France

The treatment of juxtarenal aortic aneurysms – fenestrated endografts versus chimney techniques

G. Torsello, Munster, Germany

A new multi-fenestrated graft to treat suprarenal aneurysms

P. Berg, Kevelaer, Germany

Organization of aortic services and general aspects of service reconfiguration – the UK approach

M. Thompson, London, UK

Panel discussion

19.00 GET TOGETHER with live music

8seasons Munich, Sonnenstrasse 26, 80331 Munich

7 6

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GERMAN HEART CENTER MUNICH, NOVEMBER 4 AND 5, 2011

MAC2011 MAC2011GERMAN HEART CENTER MUNICH, NOVEMBER 4 AND 5, 2011

09.00 - 10.40 SESSION V:

Acute thoracic aortic syndromes

Chairs:

F. Mohr, Leipzig, Germany M. Thompson, London, UK

KEYNOTE LECTURE:

Genetics and vascular biology in aortic dissection

D. Milewicz, Houston, USA

Functional imaging of aortic dissection by 4 D MRI flow visualization

B. Jung, Freiburg, Germany

Type A aortic dissection – current treatment strategies and future endovascular

opportunities

F. Mohr, Leipzig, Germany

Endovascular therapy of acute type B dissection: is there a need for changing definition of acute dissection?

C. Nienaber, Rostock, Germany

What is the evidence to treat intramural hematoma (IMH) and penetrating aortic ulcers (PAU) by TEVAR?

M. Czerny, Berne, Switzerland

Is there a role of FDG-PET-CT to detect unstable aortic lesions?

C. Reeps, Munich, Germany

Do we have to revascularize the left

subclavian artery also in urgent endografting of the thoracic aorta?

P. Cao, Rome, Italy

Panel discussion

10.40 – 11.10 COFFEE BREAK

SATURDAY, NOVEMBER 5, 2011

SATURDAY, NOVEMBER 5, 2011

11.10 - 12.40 SESSION VI:

Ruptured abdominal aortic aneurysms (rAAA)

Chairs:

J. Schmidli, Berne, Switzerland F. Veith, New York, USA

KEYNOTE LECTURE:

Clinical and morphological predictors of growth and rupture rates in AAAs and why a RCT comparing OR and EVAR is necessary!

J. Powell, London, UK

Open repair – in my hands the golden standard for rAAA

J. Schmidli, Berne, Switzerland

EVAR for rAAA – always my first choice (with a side note to the incidence of rAAA in Germany)

H.-H. Eckstein, Munich, Germany

Hemodynamic and coagulation management of patients with rAAA – anaesthetic

considerations

E. Kochs, Munich, Germany

Will a nationwide AAA-Screening program reduce the number of ruptured AAA? Experiences in the UK

I. Loftus, London, UK

May finite element simulation ever help to predict AAA rupture?

M. Gee, Munich, Germany

Panel discussion

12.40 - 13.00 SPECIAL LECTURE:

The misinterpretation of CREST and its misleading impact on the AHA Guidelines

F. Veith, New York, USA

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GERMAN HEART CENTER MUNICH, NOVEMBER 4 AND 5, 2011

MAC2011

SATURDAY, NOVEMBER 5, 2011

SATURDAY, NOVEMBER 5, 2011

MAC2011GERMAN HEART CENTER MUNICH, NOVEMBER 4 AND 5, 2011

Conversion to open surgery after failed TEVAR M. Jacobs, Maastricht, NL / Aachen, Germany

Extraanatomic reconstruction in thoraco-abdominal coral reef aorta

G. Fraedrich, Innsbruck, Austria

Thoracic endograft infections R. Chiesa, Milano, Italy

Permanent endovascular treatment of an aorto duodenal fistula monitored by PET-CT – is it feasible?

I. Flessenkämper, Berlin, Germany

Infected aortic grafts: autologous, in situ or extraanatomic repair?

A. Assadian, Vienna, Austria

A new surgical approach in treating graft infections after aortic surgery

J. Schmidli, Berne, Switzerland

Emergency open and endovascular redo procedure in a 19-year old boy with Marfan’s disease

U. Herold, S. Ockert, Munich, Germany

Summary of the chairmen

16.00 FAREWELL H.-H. Eckstein, Munich, Germany

R. Lange, Munich, Germany

W W W. M A C 2 0 1 1 . D E

13.00 - 14.00

Main lecture hall

LUNCH SYMPOSIUM III:

COOK Medical: Evolution Through Innovation

Multicentre study results from the BSET UK Zenith fenestrated study

S. R. Vallabhaneni, Liverpool, UK

Endovascular treatment of complicated type B aortic dissection using a composite device design: initial results from a prospective multicenter clinical trial (STABLE)

C. Nienaber, Rostock, Germany

Endovascular treatment of abdominal aneu-rysms: zenith low profile – the next generation

S. Ockert, Munich, Germany

13.00 - 14.00

Meeting room

LUNCH SYMPOSIUM AND WORKSHOP IV:

PHILIPS: Ready for the future – the Hybrid OR

A single room for all interventional procedures M. Wassenaar, Philips GmbH

Hybrid OR IT network F. Proft, Maquet GmbH & Co. KG

MAGNUS OR table – hands on S. Leidenberger,

Maquet GmbH & Co. KG 14.15 – 16.00 SESSION VII:

Monster cases, mishaps, bail outs: open and endovascular options

Chairs:

H.-H. Eckstein, Munich, Germany R. Lange, Munich, Germany

Chimneys, snorkels, sandwiches and periscopes – just bail out procedures?

M. Lachat, Zurich, Switzerland

Are bare stents for acute dissection useful to prevent end-organ ischemia?

C. Nienaber, Rostock, Germany

APTUS: a new active fixation system after EVAR H. Schumacher, Zurich, Switzerland

11 10

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GERMAN HEART CENTER MUNICH, NOVEMBER 4 AND 5, 2011

MAC2011

FACULTY

Afshin Assadian, Vienna, Austria

Jean Pierre Becquemin, Paris, France

Patrick Berg, Kevelaer, Germany

Dittmar Böckler, Heidelberg, Germany

Piergiorgio Cao, Rome, Italy

Roberto Chiesa, Milano, Italy

Martin Czerny, Berne, Switzerland

Sebastian Debus, Hamburg, Germany

Gebrine El Khoury, Brussels, Belgium

Christian Etz, New York, USA

Ingo Flessenkämper, Berlin, Germany

Gustav Fraedrich, Innsbruck, Austria

Michael Gee,Munich, Germany

Roger Greenhalgh, London, UK

Wolfgang Harringer, Braunschweig,

Gemany

Ulf Herold, Munich, Germany

Krassi Ivancev, London, UK

Michael Jacobs, Maastricht, NL /

Aachen, Germany

Bernd Jung, Freiburg, Germany

Piotr Kasprzak, Regensburg, Germany

Ali Khoynezhad, Los Angeles, USA

Eberhard Kochs, Munich, Germany

Mario Lachat, Zurich, Switzerland

Stefan Leidenberger, Maquet GmbH & Co. KG

Rainer Leyh, Würzburg, Germany

Ian Loftus, London, UK

Frank Marquardt, Bremen, Germany

Dianna Milewicz, Houston, USA

Friedrich Mohr, Leipzig, Germany

Christoph Nienaber, Rostock, Germany

Stefan Ockert, Munich, Germany

Janet Powell, London, UK

Florian Proft, Maquet GmbH & Co. KG

J. Scott Rankin, Nashville, USA

Christian Reeps, Munich, Germany

Jean Baptiste Ricco, Poitiers, France

Jürg Schmidli, Berne, Switzerland

Jessica Schmidt,Vascutek Deutschland GmbH

Hardy Schumacher, Zurich, Switzerland

Carlo Setacci, Perugia, Italy

Matt Thompson, London, UK

Giovanni Torsello, Munster, Germany

Srinivasa Rao Vallabhaneni, Liverpool, UK

Frank Veith, New York, USA

Eric Verhoeven, Nuremberg, Germany

Bernhard Voss, Munich, Germany

Mark Wassenaar, Philips GmbH

Throughout History

Certain Moments stand out

Product referenced is approved for CE Mark. Not available for sale in the U.S. Devices depicted may not be available in all countries. Check with your St. Jude Medical representative for product availability in your country.

Unless otherwise noted, ™ indicates a registered or unregistered trademark or service mark owned by, or licensed to, St. Jude Medical, Inc. or one of its subsidiaries. Trifecta, ST. JUDE MEDICAL, the nine-squares symbol and MORE CONTROL. LESS RISK. are registered and unregistered trademarks and service marks of St. Jude Medical, Inc. and its related companies.

©2011 St. Jude Medical, Inc. All rights reserved.

The Trifecta tissue heart valve is redefi ning the standard in cardiac surgery. The unique design allows the pericardial tissue leafl ets to open more fully and effi ciently in order to mimic a native heart valve. The Trifecta valve offers the closest thing to perfect performance with mean gradients in the single digits1 across all sizes – now that’s making history.

1893

Daniel H. Williams performs fi rst open heart surgery

1954 C. Walton Lillehei performs fi rst successful cross-circulation ventricular septal repair 1979

First implanted bileafl et mechanical heart valve

2010

Trifecta

TM

1. St. Jude Medical, Trifecta 400 Late Patient Year Report at six-month follow-up, January 2010.

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GERMAN HEART CENTER MUNICH, NOVEMBER 4 AND 5, 2011 MAC2011 GOLD SPONSORS SILVER SPONSOR BRONZE SPONSORS EXHIBITORS Aesculap AG Aimecs GmbH C.R. Bard GmbH CoRRect Medical GmbH Geister Medizintechnik GmbH Jotec GmbH Osypka AG Sanofi-Aventis Deutschland GmbH Sorin Group Deutschland GmbH Teleflex Medical GmbH

Trivascular Germany GmbH Vascutek Deutschland GmbH

SPONSORS AND EXHIBITORS

MAQUET Vertrieb & Service Deutschland GmbH www.maquet.com

HEMASHIELD PLATINUM

Grafts: the most used,

most studied vascular grafts. Whether the procedure re-quires a straight, one branch or multi-branch graft, HEMA-SHIELD PLATINUM is the name that means history, he mo stasis, handling and healing.

MAQUET – The Gold Standard.

HEMASHIELD PLATINUM WOVEN AORTIC BRANCH GRAFTS

DESIGNED FOR EACH TECHNIQUE

Optimal 360˚ aortic wall apposition in angulated arch anatomy without bare springs or barbs Compression resistant The only thoracic endograft engineered to perform in 6 – 33% oversizing conditions

Broad 16 – 42 mm aortic diameter treatment range Off-the-shelf tapered designs

T h e n e x t g e n e r a t i o n h a s a r r i v e d .

C O N F O R M A B I L I T Y W I T H O U T C O M P R O M I S E . www.conformabletag.com P E R F O R M A N C E b y d e s i g n

W. L. Gore & Associates, Inc. • Flagstaff, AZ 86004 • goremedical.com Products listed may not be available in all markets.

GORE®, PERFORMANCE BY DESIGN, TAG®, and designs are trademarks of W. L. Gore & Associates. ©2010 W. L. Gore & A ssociates, Inc. AP0089-EN1 JANUARY 2010

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GERMAN HEART CENTER MUNICH, NOVEMBER 4 AND 5, 2011

MAC2011

SYMPOSIA AND WORKSHOPS

FRIDAY, NOVEMBER 4, 2011 12.45 - 13.45

EVAR – Standard of Care!

Hands on workshop for Vascutek Anaconda™, presentation of the fenestrated Anaconda™ and pre-sentation of the clinical study of the Anaconda™ thoracic stentgraft

SATURDAY, NOVEMBER 5, 2011 13.00 - 14.00

Evolution Through Innovation

Ready for the future – Hybrid OR

GERMAN HEART CENTER MUNICH, NOVEMBER 4 AND 5, 2011

MAC2011

DIRECTIONS

LOCATION

The German Heart Center Munich is situated at Lazarettstrasse 36, 80636 Munich, Germany, in the heart of Munich.

You can reach the congress location…

…by public transportation

Take the underground train Line U1 from the central station to the train stop Mailingerstrasse, or take the Tram 20 or 21 to Lothstrasse. From here the German Heart Center is in walking distance.

…by car

Lazarettstrasse can be accessed directly from Nymphenburger Strasse or Dachauer Strasse. Limited parking spaces are available in front of the German Heart Center.

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GERMAN HEART CENTER MUNICH, NOVEMBER 4 AND 5, 2011

MAC2011

GENERAL INFORMATION

GENERAL INFORMATION

MAC2011GERMAN HEART CENTER MUNICH, NOVEMBER 4 AND 5, 2011

W W W. M A C 2 0 1 1 . D E

SCIENTIFIC ORGANISER

Univ-Prof. Dr. med. Hans-Henning Eckstein Klinikum rechts der Isar

Technical University of Munich Department for Vascular Surgery

Ismaninger Strasse 22, 81675 Munich, Germany Prof. Dr. med. Rüdiger Lange

German Heart Center Munich Technical University of Munich

Department for Cardiothoracic Surgery Lazarettstrasse 36, 80636 Munich, Germany

CONGRESS ORGANISATION

KelCon GmbH Regina Uihlein

Liebigstrasse 11, 63500 Seligenstadt, Germany Phone: +49 6182 94 666 32; Fax: +49 6182 94 666 44 r.uihlein@kelcon.de; www.kelcon.de

LOCATION

German Heart Center Munich (DHZ)

Lazarettstrasse 36, 80636 Munich, Germany

REGISTRATION FEE

Registration until October 15, 2011 EUR 300,00 Registration from October 16, 2011 EUR 350,00 Fellows, Nurses and Medical Technicians EUR 150,00

Students free of charge

Food and beverage is included in the registration fee as well as 1 ticket for the

get-together on Friday evening. For registration please use the website www.MAC2011.de or the attached registration form.

CANCELLATION POLICY

Cancellations are required in writing. Cancellations will be charged with the full registration fee.

GET-TOGETHER

Friday, November 4, 2011, starting at 19:00 8seasons Munich

Sonnenstrasse 26, 80331 Munich Dress Code: business casual

Admission is included in the registration fee – we are looking forward to welcoming you.

ACCREDITATION

This is a CME (Continuing Medical Education) accredited conference and you will receive CME points from the Bavarian Medical Association.

LANGUAGE

The official congress language of the meeting is English.

19 18

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Below the knee

Maris Deep / Chromis Deep

Stents Amphirion Deep Balloon KiteWire Deep Guidewire IN.PACT Amphirion Drug-Eluting Balloon

Endovascular Competence.

Valiant® Captivia Stent Graft Thoracic Aorta Endurant® Stent Graft Abdominal Aorta Femoral Maris Plus Stent Admiral Xtreme Balloon IN.PACT Admiral Drug-Eluting Balloon Kidney Hippocampus / Racer RX Stents

Innovating for life.

Carotid Cristallo Ideale Stent Submarine Rapido Balloon Piton GC Guiding Catheter

MO.MA Ultra / Fibernet

Protection Device

Iliac

Scuba / Assurant Cobalt / Complete SE / Maris Plus

Stents Admiral Xtreme Balloon Universal Pioneer Plus Re-Entry Catheter Reef

High Pressure Balloon

Reliant®

Stent Graft Balloon

Knee

Pacifi c Xtreme

Balloon

IN.PACT Pacifi c

References

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