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OUTCOMES

2008

DIVISION OF MEDICINE

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About Cleveland Clinic Florida

Cleveland Clinic Florida’s medical staff are dedicated physicians who have joined the clinic as

salaried doctors to practice a different kind of medicine: Where commitment to patients,

providing expert innovative care, and involvement in medical education are the goals.

We work as a team, access the same electronic medical records, and cooperate to give our

patients the best care.

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Department of Pulmonary and

Critical Care Management

Staff

TABLE OF CONTENTS

:

Overview

4

Staff

5

Innovation

7

Outcomes

11

Eduardo C. Olivera, MD

Frank Rahaghi, MD

Jose Ramirez, MD

Laurence A Smolley, MD

2008

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2008

Overview

• Pulmonary and Critical Care Department

The Department of Pulmonary Medicine, Critical Care Medicine and Sleep Medicine specializes in the diagnosis and treatment of patients with illnesses that affect the lungs, breathing and sleep. Cleveland Clinic Florida’s specialists diagnose and treat

diseases such as asthma, bronchitis, lung cancer, acute and chronic respiratory failure, pulmonary hypertension, sleep disorders such as sleep apnea and narcolepsy, chronic obstructive pulmonary disease (COPD), and lung infections.

Pulmonologists collaborate with colleagues in Cardiothoracic Surgery, Cardiology, Hematology/ Oncology, Infectious Diseases, Rheumatology and surgeons in other specialties to provide

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2008

Staff

Laurence A. Smolley, MD

Specialty Interests

Lung cancers; asthma; breathlessness; sleep disor-ders such as snoring, excessive daytime sleepiness, obstructive sleep apnea and narcolepsy.

College Education

B.S. (chemistry), Yale University, New Haven, CT, 1972

Medical Education

M.D., New York University School of Medicine, New York, NY, 1976

Advanced Training

Downstate-Kings County Medical Center, Brooklyn, NY (internal medicine residency)

Jackson Memorial Hospital/University of Miami, Miami, FL (pulmonary fellowship)

Professional Experience

University of Miami School of Medicine, Miami, FL, Assistant Professor of Medicine, 1981-1986

Miami Veterans Administration Hospital, Miami, FL, Acting Chief, Pulmonary Section, 1983-1984; Chief, Pulmonary Section, 1984-1986

Baptist Medical Center, Jacksonville, FL, Director, Pulmonary Rehabilitation, 1986-1994; Medical Director, Sleep Disorders Center, 1986-1994 Cleveland Clinic Florida Weston, staff, Dept. of

Pulmonary Medicine, 1995-present; Chairman, Dept. of Pulmonary Medicine, 1999-present; Medical

Director, Sleep Disorders Center, 1997-present

Certification

American Board of Internal Medicine, 1982 Subspecialty in pulmonary diseases, 1984

Subspecialty in critical care medicine, 1989, 1999 American Board of Sleep Medicine, 1988

Eduardo C. Oliveira, MD

Specialty Interests:

Lung cancer; asthma and sleep disorders; lung fibrosis; critical care medicine; interventional bron-choscopy

Medical Education

M.D., Medical College of Teresopolis, Rio de Janeiro, Brazil, 1992

Advanced Training

Washington Hospital Center, Washington, DC (residency)

George Washington University, Washington, DC (pulmonary and critical care fellowship)

Professional Experience

Washington Hospital Center, Washington, DC, Staff Physician, 1997-2001

Cleveland Clinic Florida, staff, Dept. of Pulmonary Medicine, 2001-present; Medical Director, Intensive Care Unit, 2002- present

Certification

American Board of Internal Medicine, 1997 Subspecialty, Pulmonary Medicine, 2000 Subspecialty, Critical Care Medicine, 2001

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2008

Franck Rahaghi, MD, MHS, FCCP

Specialty Interests

Pulmonary hypertension; interstitial lung diseases, including: collagen vascular diseases and pulmonary fibrosis; critical care

College Education

B.S. (biomedical engineering), University of Califor-nia, San Diego, CA, 1991 (with honors)

Graduate Education

M.H.S. (health policy), University of California, Berkeley, CA, 1994

Medical Education

M.D., University of California, San Francisco, CA, 1996

Advanced Training

University of Minnesota, Minneapolis, MN (internship)

University of Illinois, Chicago, IL, (residency)

New York Presbyterian-Weil Cornell Medical Center, New York, NY (pulmonary/critical care fellowship)

Professional Experience

Cornell University-Weil School of Medicine, New York, NY, Instructor in genetic medicine, 2001 Sharp Memorial Hospital, San Diego, CA, Hospitalist, 2000-2001

Cleveland Clinic Florida Weston, staff, Dept. of Pulmonary Medicine, 2003-present

Certification

American Board of Internal Medicine, 1999 Subspecialty in pulmonary diseases, 2002 Subspecialty in critical care, 2003

Jose Ramirez, MD

Specialty Interests

Sleep disorders: sleep apnea, narcolepsy, insomnia, and restless leg syndrome; critical care; lung cancer; asthma; COPD

Medical Education

M.D., Universidad Libre de Cali, Clinica Rafael Uribe, Cali, Colombia, 1996

Advanced Training

University of Miami, Jackson Memorial Hospital / Veterans Administration Medical Center / Mount Sinai Medical Center, Miami, FL (internal medicine internship and residency, fellowship in pulmonary medicine and critical care, and sleep disorders fellowship)

Professional Experience

San Vincente de Paul Hospital, staff, Dept. of Medical Social Services, Palmira, Colombia, 1996-1997

South Medical Center of Colsantis Health Institution, staff, Emergency Room, Cali Colombia, 1997-1999 Cedars Medical Center, Miami, FL, staff, Dept. of Critical Care, 2005-2006

Cleveland Clinic Florida, staff, Dept. of Pulmonary Medicine and Dept. of Sleep Disorders,

2006-present

Certification

American Board of Internal Medicine, 2002 Subspecialty in Pulmonary diseases, 2004 Subspecialty in critical care, 2005

American Board of Sleep medicine, 2006

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2008

Innovation

• Research and Research Fellowship

We have now established a research fellowship in pulmonary medicine with emphasis in teaching methodology and research principals.

We have graduated 4 fellows to date with an ongoing roster of 2 fellows at a time.

Recipient of Betty and Stuart Hamilton 2.2 million dollar grant for research and resources.

A variety of abstracts/ articles have been produced through the hard work of our fellows:

2009 The Impact of Including a Physician Alert Accompanying Pulmonary Function (PFT) Results on Testing for and Detection of Alpha-1 Antitrypsin Deficiency. Franck Rahaghi, MD, MHS, Ismael Ortega, MD, Nicholas Rahaghi, Ph.D., Eduardo Oliveira, MD, Jose Ramirez, MD, Laurence Smolley, MD, James K. Stoller, MD, M.S (accepted: Journal of COPD Sept 2008)

2008 Number of COPD Patients Needed to Test to Find an Alpha-1 Antitrypsin Deficient Patient at 95% Certainty. F. Rahaghi, MD, MHS, J. Zamudio, MD, MBA, I. Ortega, MD,

E. Oliveira, MD, J. Ramirez, MD and L. Smolley, MD. Cleveland Clinic Florida, Weston/Fort Lauderdale, FL, United States and 2Alpha Foundation, Miami, FL, United States. Accepted ATS 2008

2008 Role of BNP in Identifying Elevated

Pulmonary Wedge Pressure in Patients with Pulmonary Hypertension. V. Navas, MD, N. Rahaghi, PhD, J. Ramirez, MD, L. Smolley, MD, E. Oliveira, MD, M. Areces, MD, C. Scridon, MD, K. Fromkin, MD, G. Novaro, MD and F. Rahaghi, MD, MHS. Cleveland Clinic Florida, Weston/ Fort Lauderdale, FL, United States and University of California, San Diego, CA, United States. Accepted ATS 2008

2007 Lack of documented consideration of activated drotrecogin alfa infusion in septic patients. Lior, Shamai DO, MPH, Rahaghi, Nicholas, PhD, Ramirez, Jose MD, Oliveira, Eduardo MD, Smolley, Laurence, MD, Rahaghi Franck M.D. M.H.S. ATS 2008 2007 Accelerated hemodynamic decompensation

of young patients prior to death in the

Intensive Care Unit. Martinez NP, Rahaghi NF, Rahaghi, FF SCCM 2008

2007 A Cost Analysis of the Treatment of

Pulmonary Arterial Hypertension. Farhan Abid, MD, Osmel Delgado PharmD, Franck Rahaghi, MD, MHS.

• Interventional Bronchoscopy Service

The following services are offered: • Laser Bronchoscopy/

Tumorablation

• Brachytherapy catheter placement • Stent placement

• Thorcacoscopic evaluation of pleura for biopsy and pleurodesis

• Endo-Bronchial ultrasound needle biopsy for much improved yields in lymph node biopsies.

This service, directed by Dr. Oliveira is the only one of its kind the Broward County.

• Thoracic Surgery Service

At the end of 2006, Cleveland Clinic Florida launched its new Section of Thoracic Surgery and new comprehensive Multidisciplinary Thoracic Oncology program. The multidisciplinary team is composed of a thoracic surgeon, pulmonologists, medical and radiation oncologists, radiologists, pathologists, gastroenterologists, and numerous support staff. Together they specialize in the diag-nosis and treatment of lung and esophageal cancer as well as other thoracic malignancies such as chest wall tumors, thymic tumors, and lymphoma.

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2008

The Section of Thoracic Surgery is pleased to offer its patients new innovative treatments such as pho-todynamic therapy (PDT). For patients with cancer in the main airways or in the esophagus who cannot undergo surgical resection, PDT is an endoscopic (no incisions) light-based treatment used to destroy the tumor. This typically involves a few outpatient treatments over one week and allows patients to breathe or swallow easier depending on the location of the tumor.

In conjunction with the Interventional Pulmonary service, tracheobronchial stenting can be used when there is airway obstruction from a variety of causes. Other new thoracic surgical services include:

• Thoracoscopic lung biopsy for interstitial lung disease with an average length of stay of less than 24 hours.

• Thoracoscopic sympathectomy for hyperhidrosis. This is performed on an outpatient basis.

• Thoracoscopic decortication for empyema or parapneumonic effusion.

• Thoracoscopic first rib resection for thoracic outlet syndrome.

• Thoracoscopic resection of mediastinal masses including thymectomy for myasthenia gravis. For patients with tumors in the major airways, a lung-sparing procedure called “sleeve lobectomy” may be utilized to preserve pulmonary function. In the past, the surgical alternative would have been a pneumonectomy—the removal of the entire lung. In conjunction with the Division of Radiation Oncol-ogy, stereotactic radiosurgery is used to treat certain thoracic malignancies. This new modality provides great accuracy and precision in the delivery of radia-tion to the planned target with fewer treatment ses-sions than more traditional external beam radiation. Corroborating with the Division of Interventional Radiology, radiofrequency ablation may be used to treat lung tumors in patients who are not candidates for surgery. This allows for a minimally invasive ap-proach to the treatment of primary and metastatic lung cancers.

The Section of Thoracic Surgery is pleased to offer these latest advances in the management of chest disorders to the patients of South Florida. Approxi-mately 90% of our procedures are performed mini-mally invasively with relatively brief hospitalization. For a consultation with the Section of Thoracic Sur-gery, please call 954-659-5321.

• Bronchoscopic Intubations

When the body is in distress, at times, it is neces-sary to insert a tube into the

airways to assist the patient with breathing. Usually this procedure is performed by direct visualization and in-sertion of the endotracheal tube. Our pulmonologists use special scopes to insert

endotracheal tubes resulting in a 100% success rate in incubation, with less trauma to the patient and decreased need for sedation.

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2008

Innovation

• Pulmonary Hypertension Clinic

The only Clinic in Broward and Palm Beach counties, the Pulmonary Hypertension Clinic provides comprehen-sive diagnostic and treatment services for patients with pulmonary hypertension. The hospital and the staff are familiar with PH patients. Proce-dures that are denied in other hospitals due to lack of staff familiarity are successfully performed in our institution. We provide expert echocardiographic testing, right heart catheterization with reversibility testing on nitric oxide, specialized and dedicated nursing support services and readily accept trans-fers from outside hospitals of patients in need of specialized care. The Pulmonary Hypertension Clinic is under the direction of Dr. Rahaghi. He is a nation-al speaker in the field of pulmonary hypertension, with multiple ongoing research projects.

• Pulmonary Education

There is clear evidence that pulmonary rehabili-tation decreases com-plications of COPD and increases patient well-being.

The pulmonary department continues to support an active rehabilitation and exercise program for patients with lung disease. In conjunction with the rehabilitation educators, we are offering a unique blend of pulmonary education services in the clinic. They include:

• Disease state teaching in COPD, Emphysema, and asthma

• Inhaler, peak flow, spacer teaching.

• Asthma action plan and COPD contingency planning

• Pulmonary rehab evaluation

• Smoking cessation clinic, using state-of-the-art techniques.

• Incentive spirometry teaching and exercise planning to decrease complications prior to cardiac surgery.

Pulmonary rehabilitation, asthma action plans and disease state teaching have all been shown to de-crease morbidity of pulmonary diseases.

• Smoking Cessation Clinic

Staffed by trained respiratory therapists, this comprehensive clinic, provides multiple vis-its, support, medication and guidance to patients- under the supervision of a pulmonary physician.

State-of-the-art techniques and

the latest medications are used to end nicotine ad-diction. The services are billed to insurances. Psychotherapy and Acupuncture are also available, some on a fee basis.

• Sleep Disorders Center

Our Sleep Disorders Center is one of two certified centers in Broward County. We recently expanded the lab to 6 beds and relocated to the Marriot Hotel. By moving to a hotel setting, we seek to provide an environment more conducive to sleep, and greater comfort to the patients.

Our Sleep Lab is backed by two sleep board certified physicians. The latest technol-ogy, and utmost care is our standard. Multiple research projects are ongoing in the sleep

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2008

Innovation

• Pulmonary Function Laboratory

Our comprehensive Pulmonary Function lab is equipped with a Body Box set-up that allows more accurate lung volume measurements and allows for flight simulation in patients with borderline respira-tory status pre-flight. The volume of the pulmonary function tests has been robust over the years. • Special services include:

• Flight simulation • ABG

• Methacholine challenge test • 6 min walk test

• Alpha-1 Antitrypsin testing • Overnight Saturation Study

• ICU

Aside from applying the latest in technology, our ICU is particularly innovative in the following dimensions: • Use of ultrasound guidance in all ICU procedures, including thoracenthesis and central line

placement.

• Multidisciplinary rounds with collaboration of an extensive ICU team: Board certified ICU attending medical residents, interns, medical students, respiratory therapists, ICU nurses, nursing

students, pharmacists, pharmacy students, case managers, and dietitians. This group approach improves decision making and facilitates collaborative execution of the plans.

• The academic residency programs, in conjunction with cardiology, gastroenterology, and renal fellowships drive excellence. As repeatedly

demonstrated, hospitals with academic programs have an overall decrease in mortality.

• Continued education of the nursing staff by medical educators.

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2008

Outcomes

We are here to care for the patients:

This attitude drives our everyday activities.

In the pulmonary department, most of our patients are satisfied or very satisfied with us, and most will recommend us to their family and friends: In fact, word of mouth has been one of the sources of patient referral to us in the last few years.

These are results of an independent survey of our pulmonary department physicians:

Our patients are extremely satisfied with the care they receive at our Clinic:

Our sleep lab experience is second to none, as evi-dent by constant appreciation and accolades from the patients in exit surveys, the morning after:

• 100% of patients would recommend the Sleep Center to family and friends:

Did you find the room comfortable and pleas-ant Was the bed comfort-able? Were the technolo-gists pleasant? Would you recommend our Sleep Center? 4.63/5 4.51/5 4.81/5 100% Yes

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2008

Outcomes

• ICU Coverage

Multiple studies have demonstrated that Intensive Care Units where there is 24 hour in-house coverage have substantially lower mortality rates. Our hospital is one of few in Broward county with 24 hour cover-age by fellowship trained and board certified inten-sivists. This is indeed reflected in our decreased mortality and average length of stay.

• Quality of Care

We simply provide better care:

Lower mortality rates achieved in combination with decreased length of stay shows our commitment to our patients:

This represents a 68% decrease in mortality and a 15% decrease in mortality vs. US average.

Our ICU is recognized as fully dedicated to the principles of the Leapfrog Initiative (A health care payer supported group that seeks to propagate quality care).

• Care of Pneumonia Patients

The Center for Medicare and Medicaid Studies con-tinuously monitors hospitals for their performance in the care of pneumonia patients. The following table is the most recent report of Cleveland Clinic Florida, released in December of 2008.

Cleveland Clinic Florida is routinely beating national and local standards for care of pneumonia patients.

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2008

Outcomes

• Interventional Pulmonology

Historically we have had excellent results in interven-tional procedures with excepinterven-tional success rates.

• BBBB

This year we have continued excellence in our out-comes:

The EBUS procedure (Endotracheal Biopsy under UltraSound) performed at Cleveland Clinic has been particularly successful in providing the referring physicians with a diagnosis on enlarged/ diseased lymph nodes.

Overall, in the last year we have had great results with our interventional and diagnostics procedures:

• Sleep Center

Our sleep center, now located atop the Marriott Hotel in Weston, offers state-of-the-art facilities de-signed both for accuracy and comfort. The number of patients going through the center is continuously increasing.

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2008

Outcomes

• Pulmonary Function Laboratory

In addition to expansion of services, the PFT lab has been a major site for research in the fields of Alpha-1 Antitrypsin deficiency.

• Pulmonary Hypertension Clinic

The Pulmonary Hypertension Clinic has evolved into the busiest such practice in the counties of Broward, Palm Beach and Collier, serving the major cities of Fort Lauderdale, Boca Raton, Palm Beach

and Naples:

Our center is recognized by the Pulmonary Hyper-tension Association and featured on their web page. Active treatment: 105 patients by Dec 2008

Multiple research trials are ongoing:

• Clinical Resource Centers

There are over 50 Clinical Resource Centers through-out North America that specialize in patient care and education for those with Alpha-1 Antitrypsin Deficiency (Alpha-1). Some Centers treat lung disease and others treat liver disease. Centers have other resources for Alphas such as support groups, transplant centers and pulmonary rehabilitation. Please contact the center nearest you for

References

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