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Matrix architecture defines the preferential localization and migration of T cells into the stroma of human lung tumors

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Figure

Figure 1T cells preferentially migrate into the tumor stroma. (A) Preactivated T cells (Hoechst; green) were added to a human lung tumor slice that
Figure 2T cells are able to infiltrate tumor islets expressing CCL5. (A) SEM images of 2 different tumors from lung cancer patients, showing cohesive tumor cells
Figure 3T cell migration within human lung tumor slices is partially inhibited by PTX
Figure 4Matrix fiber density strongly influences the localization and migration of T cells
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