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Conditional knockdown of DNA methyltransferase 1 reveals a key role of retinal pigment epithelium integrity in photoreceptor outer segment morphogenesis

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Academic year: 2020

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Figure

Fig. 1. Characterization of Dnmt1mutants. fl/fl:Rx-Cre/+(A) Control and mutant Dnmt1
Fig. 2. Thin retinal layers and absence ofphotoreceptor outer segments in
Fig. 3. Altered distribution of heterochromatin,euchromatin and DNMT1 in Dnmt1 mutant
Fig. 4. Defects in photoreceptor maturation and lack of S-cones in Dnmt1 mutant retina
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