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Intracellular trafficking of factor VIII to von Willebrand factor storage granules

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Figure

Figure 1. Intracellular processing of FVIII in transfected AtT-20 cells. Plasmid constructs encoding the human FVIII cDNA were tran-siently transfected into various cell lines, and the resulting protein ex-pression was analyzed after immunoprecipitation
Figure 3. Functional analysis of the FVIII-binding capability of AtT-20 expressed vWf
Figure 4. Intracellular distribution of vWf and FVIII in AtT-20 cells. Stable AtT-20 cells were transiently transfected with either pCI-Neo or WTvWf plasmids
Figure 5. Comparison of the FVIII and vWf expression levels in vWf (vWf:Ag), and are shown along the dual transfected FVIII/AtT-20 cells
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