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Targeting hypoxic cancer stem cells (CSCs) with Doxycycline : implications for optimizing anti angiogenic therapy

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Figure

Figure 1: Experimental approach. To understand the mechanism(s) underpinning the effects of hypoxic stress on CSC propagation, we used an unbiased metabolic phenotyping approach
Figure 3: Mammosphere formation is reduced after acute hypoxia and increased after prolonged hypoxia
Figure 4: Doxycycline inhibits the formation of mammosphere induced by prolonged hypoxia
Figure 5 directly demonstrates that a significant
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