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The commercial pig as a model of spontaneously occurring osteoarthritis

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Figure

Fig. 1 Development of lameness as a marker of behavioural pain. Ascoring system was used to assess lameness as a marker ofbehavioural pain
Fig. 2 Spontaneous development of joint damage in the commercial pig.joints from juvenile, adult, and older adult animals.medial and lateral compartment within same age group, as determined using Kruskal-Wallis non-parametric test
Fig. 3 Areas of cartilage damage exhibit proteoglycan loss. a Representative images (10X magnification) of Safranin O staining of proteoglycan infemoral medial condyle cryosections from n = 8 adult pigs with varying signs of joint damage
Fig. 4 Characterisation of porcine chondrocytes and cartilage explant.represent mean ± SEM (=stimulation of porcine non-damaged cartilage explant from older adult pigs with recombinant IL-1B
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