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Integration of zebrafish fin regeneration genes with expression data of human tumors in silico uncovers potential novel melanoma markers

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Academic year: 2020

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Figure

Figure 1: (A) Regenerating zebrafish tissue used for gene expression analysis. (B) Gene selection pipeline leading to the identification of novel melanoma overexpressed genes.
Table 1: Fifty-four genes (detected by 71 probes) were significantly overexpressed at least 4-fold in regenerating blastema compared to normal fins
Figure 2: (A) Gene products for melanoma overexpressed genes were screened for staining in patient melanoma using the Protein Atlas database
Figure 3: Five genes of the Oncomine angiogenesis gene signature were co-regulated with Bambi transcripts in melanoma compared to other cancers (> 1.5-fold-change, p < 0.001)
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